Our focused libraries are designed to modulate biological targets while adhering to drug-like or lead-like criteria.  This intelligent design results in higher quality compounds that lead to the faster generation of new clinical candidates.  The SoftFocus libraries include drug-like molecules ion channel, kinase, and GPCR targets and have been extended to include Azetidine and C-nucleoside collections based on novel cores of biological interest.  Our novel ThemePair libraries are composed of low molecule weight compounds with lead-like properties suitable for conventional and high concentration screening.  These libraries can be used in combination with our assay development and screening expertise conduct an efficient hit-finding campaign.  

By applying our in-house molecular informatics expertise, we can also design and synthesize high-quality exclusive compound libraries for primary screening, lead optimization and patent exemplification.

These target screening libraries are complemented by our natural product libraries, which provide unsurpassed chemical diversity and strong physiochemical advantages over de novo synthesized molecules.