Our SoftFocus libraries are rationally-designed focused compound sets that modulate biological targets whilst adhering to drug-like or lead-like criteria.
The SoftFocus range of libraries has led to:
preclinical/clinical candidates in a variety of therapeutic areas
>100 patents for our clients
numerous publications in peer reviewed journals
14 client-published co-crystal structures in the protein databank
tool compounds for new areas such as epigenetic targets and protein-protein interactions
The intelligent design uses a range of proprietary chemogenomic technologies and advanced computational techniques. Each library is built to give critical structure-activity relationship (SAR) information, direct from biological screening and so enables faster generation of new clinical candidates.
Our SoftFocus libraries can be accessed through our subscription model.
Resynthes is offered for SoftFocus libraries. Price is quoted on a case by case basis with discounts for larger numbers of compounds. Typical turnaround time is two weeks depending on the complexity of the chemistry. Please contact us to request a quotation.
For more information on how to access our SoftFocus libraries or to learn more about their success, please use the links below or contact us.