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Assay development
We have extensive target class and disease area expertise and provide access to comprehensive assay development services. In combination with our small molecule compound collection and natural product libraries we offer a complete package for your early stage drug discovery programs.
Our services include custom assay development, assay formatting for high-throughput screening, compound screening assays for hit finding and hit-to-lead and lead optimization.
If you would like to know more about our assay development capabilities please contact us.
Assay specifics
- Use of human primary cells in our Primepath platform
- Medium- and high-throughput
- High-content and multi-parameter
- Automated and conventional electrophysiology
- Compound profiling
Over 450 assays developed over a range of target classes; in particular biochemical and cellular assays for ion channels, kinases and G-protein coupled receptors.
We have developed disease-relevant assays in human primary cells for:
- Inflammatory diseases
- Bone and joint diseases
- Respiratory diseases
- Neurodegenerative diseases
- Obesity and diabetes
- Oncology
We provide state-of-the-art screening technologies:
- Electrophysiology, including automated patch-clamp and conventional techniques
- Fluorescence-based
- High-content and detection of multiple parameters
- “Lab on a chip” microfluidic kinase profiling
- High-throughput plate imaging
- Radioisotopic assays
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