Back
Natural products
We use the latest advances in discovery technology to find hit and lead molecules from fungi and actinomycetes. Natural products have long been a major source of new medicines, agrochemicals and animal health products. Natural product based compounds offer potency against a broad range of biological targets, high diversity and very desirable physicochemical properties.
If you would like to know more about our natural products please contact us.
Our platform provides:
- Over 125,000 natural product sub-fractions, each containing on average 10-20 compounds, derived from microbial fermentations of a subset of our exclusive collection of 45,000 actinomycetes and 8,000 fungi
- High-throughput screening of natural product sub-fractions from microbial fermentations, followed by isolation and rapid structure elucidation of the active compound
- Over 500 pure natural compounds, many unavailable elsewhere, acting on specific target classes (including inhibitors for HSP90, kinases and proton-ATPases), interacting with specific pathways (such as apoptosis, angiogenesis and immunosuppression) together with cytotoxic and antimicrobial compounds
- Expertise in performing tailored fermentations and compound production
- A track record of lead optimization and profiling studies with proven results
- Over 35,000 as yet unexploited actinomycetes and fungi
Print to HTML
Print as PDF
Send to a friend