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Adenoviral technology
Adenoviruses are used to insert cDNA or shRNA into cells in order to switch genes of interest off (knock-down) or on (knock-in). We have collections of arrayed adenoviruses focusing on drugable targets, greatly increasing the chances of discovering clinically significant compounds. Our knock-down collection also includes antibody targets.
SilenceSelect collection
The SilenceSelect collection consists of over 11,500 shRNAs that can be used to knock-down 5,000 different human drugable targets. All the protein classes that are considered to be affected by small-molecule drugs are well-represented in the collection.
Because shRNA is expressed in human cells over a long period (10 days), complex assays including cell differentiation can be carried out using the SilenceSelect collection.
FLeXSelect collection
FLeXSelect is a collection of over 1,900 full-length cDNAs that can be used to enhance the expression of genes in cells.
If you would like to know more about our adenovirus collections please visit our new FLexSelect and SilenceSelect website. Alternatilvely contact us.
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