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High-content screening

Our intelligent screening platform combines high-content screening with disease-relevant assays in human primary cells, to give more detail on the effect of proteins and small molecules on cellular activities related with disease. This technique is particularly useful in small molecule mechanism-of-action studies and disease pathway analysis.

If you would like to know more about our services, discuss custom assays, specific research, or get a quote, please contact us.

Successful screening

Our proprietary algorithms, and know-how of disease biology, allow us to make the right selection of parameters to be measured before screening starts. High content screening is a very powerful technology for both initial screening and subsequent validation steps.

We have extensive experience in setting up assays and generating in-house algorithms to analyze:

  • Anchorage independence
  • Cellular toxicity
  • Cell motility and migration
  • Cytoskeletal rearrangements
  • Differential protein expression and translocation
  • Inclusion body formation
  • Neurite outgrowth
  • Protein aggregation
  • Protein expression
  • Tubulogenesis
  • Viral replication




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BioFocus®, SoftFocus®, Galapagos®, SilenceSelect® and FLeXSelect® ThemePair™, FieldFocus™, HDRA™. Helical Domain Recognition Analysis™, 2D Roadmap™, Thematic Analysis™, SFK™, SFI™, SFG™ and PrimePath™ are trademarks of Galapagos NV and/or its affiliates.